CBD and Melatonin – The Perfect Pair for Sleep?

CBD and Melatonin

When it comes to getting a good night’s rest, many of us struggle with sleep disorders that keep us from feeling rested and refreshed.

This can lead to weaker immune systems, increased risk of depression or anxiety, and other damaging consequences. Although pharmaceutical sleep aids may be an option for some, many are turning to natural alternatives that won’t have long-term side effects. Combining CBD and melatonin is becoming the natural alternative of choice for achieving better sleep with fewer associated risks.

In this article we will explore how CBD and melatonin work together to revolutionize our quality of sleep like two pieces of a puzzle – creating something larger than what could be possible with either one in isolation.

What Is CBD?

Cannabidiol (CBD) is a naturally occurring cannabinoid found in hemp and marijuana plants.

Various studies have found evidence that it can induce relaxation, reduce overall anxiety levels, and provide pain relief – along with many people hailing it as a natural sleep aid.

It is available in multiple forms such as CBD oils, capsules, tinctures, edibles, topicals, and more. CBD has potential medicinal uses but keep in mind that it is a supplement, not a cure.

What Is Melatonin?

Melatonin is a naturally occurring hormone found in the body that helps regulate sleep by signaling our brains when it’s time to sleep. Taking a melatonin supplement (available OTC) can help induce quality sleep when taken the right way.

That being said, melatonin does have some potential side effects such as daytime grogginess, headaches, and irritability; thus, it should be used with caution.

Also, keep in mind that although there has not been a direct link between CBD and drug interactions, taking too much of either can result in unwanted effects, more so with melatonin. Potential side effects from melatonin include: 

  • Headaches  
  • Irritability  
  • Dry mouth  
  • Morning Fatigue 
  • Changes in Appetite
  • Grogginess during the day 

How Does Melatonin Help You Sleep?

Melatonin is a naturally occurring hormone found in our bodies that helps to regulate sleep. By interacting positively with our body’s circadian rhythm, melatonin sends signals out to our brains to indicate when it’s time for rest and recovery. 

The pineal gland is responsible for producing melatonin, along with a hormone called serotonin, which is another hormone that helps to regulate mood and stress levels.

Used appropriately in the form of a supplement about 30 minutes before bedtime, melatonin can help induce a more restful state by increasing serotonin levels and affecting receptors found in the brain.

Two images one restless awake and one sound asleepExploring CBD’s Effects on Sleep

Just as melatonin interacts with receptors in our brain to initiate sleep, CBD has its own way of helping to promote a restful state. Specifically, CBD helps reduce stress hormones and balance mood levels by interacting with our endocannabinoid system (ECS).

The ECS helps to maintain homeostasis in our body by binding onto receptors found throughout the body and sending signals out as needed.

As an example, when CBD binds to cannabinoid receptor type 1, it helps fight inflammation from within while also reducing serotonin levels which can help improve quality of sleep.

Understanding REM Cycles

REM (rapid eye movement) sleep is a vital part of keeping both our physical and mental bodies healthy.

We spend around 20-25% of total sleep in the REM cycle where our brains consolidate the memories made during the day while the body repairs stressors encountered throughout the day.

Too little REM sleep could be damaging to our health in multiple ways, but when combined with CBD and melatonin in moderation, it can result in higher quality restorative sleep cycles.

During our REM sleep cycles, we traverse through multiple states of consciousness and experiences.

The content of dreamscapes evolve over the course of the night, from short episodes to longer and more vivid dreams.

As the night goes on, cognitive skills such as problem solving and decision making in these dream states improve as our brains rewire neural networks for improved behavior when we wake up.

When combined with CBD products, this can provide a stronger overall restorative benefit without having negative consequences on the length or quality of your REM cycle.

How Does CBD Help REM Sleep?

CBD helps reduce stress hormones like cortisol and balance mood levels, thus promoting relaxation and enabling an easier transition into a restful state. Our endocannabinoid system (ECS), plays a key role in regulating our sleep-wake cycles.

Research suggests that CBD’s incredible capacity to regulate the activity of our ECS is like installing a dimmer switch in a room – it helps our body gauge how much ‘light’ it needs to rest and recharge.

With the right combination of CBD products and melatonin, we might quiet down that light until it’s just bright enough to get the job done – aiding our body’s transition from wakeful moments into deeper restorative sleep.

Combining CBD and Melatonin for Better Sleep

Just like how yin and yang can work together in perfect harmony to create something greater than what could be achieved in isolation, the combination of CBD and melatonin may also be synergistically powerful.

This natural blend might represent the best solution to tackling any sort of sleep disorder.

While melatonin works on the brain’s receptors, creating signals that help your body recognize it’s time for rest, CBD has its own way of reducing anxiety levels inducing a calm and relaxed state.

CBD + Melatonin Blends

Should you go with a blend of these natural ingredients, or use them separately?

CBN Oil Drops

We suggest taking them separately as they both complement each other. One of the major issues with a combined blend is that any people who have trouble sleeping have already tried melatonin. 

If you are already taking melatonin supplements, CBD products for sleep are an excellent way to compliment that.

The second issue is that melatonin dosing varies greatly depending on the individual. As a result, establishing a standard concentration – a one-size-fits-all approach – is simply ineffective. 

Some people may find it too high, while others may find it too low. Melatonin is a good supplement, but we encourage people who want to try it to incorporate it into their goodnight routine and, more importantly, to experiment to find the best dose that works for them – without interfering with sleep patterns. 

Our proprietary sleep blend instead combines CBD with a higher concentration of another little-known cannabinoid called CBN, which is known for its sleep boosting properties.

Finding the Right Dosage

When it comes to finding the right dosage of CBD and melatonin, it’s important to keep in mind that what works for one person may not work for another.

Manipulating Your Circadian Rhythm with Melatonin

Melatonin has been known to interact positively with our body’s natural circadian rhythms by sending signals out that indicate its time for bed.

However, using too much of it could lead to a disruption in your internal clock – ultimately having the opposite effect than was intended.

Therefore, keep an eye on your dosages until you understand how your own internal body cycles react.

Two dogs and a cat playing with tennis ballsPets Can Benefit from CBD and Melatonin Too!

It’s not only humans who can benefit from the combined use of CBD and melatonin—our pets can too! For instance, CBD for cats can help manage their anxiety levels and CBD Oil for dogs can help our pups find rest easier; this natural combination may offer relief without the risks associated with other common sleep medications.

Our own beloved pet family loves our full spectrum CBD oil for dogs and cats.


When it comes to improving the quality of sleep with natural supplements, pairing CBD oil with melatonin may be just what you need for optimal slumber. Evidence suggests that when taken together, these two substances have a synergistic effect which works together to reduce stress levels and create a deep, restorative sleep cycle. 

Used correctly, this combo could provide maximum restorative benefits without all the risks associated with typical sleeping medications!

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